Silicon photonic chip-based biosensor for COVID-19 and flu detection with high sensitivity and specificity

Since the end of 2021, Omicron, the new variant of SARS-CoV-2, has continued to spread as the predominant strain of COVID-19. Compared to previous variants, Omicron causes milder symptoms, which are similar to symptoms of other common respiratory infections, such as flu. In this work, we develop a silicon photonic chip-based biosensor for COVID-19 and flu detection using subwavelength grating micro-ring resonator. The biosensor realizes the detection of two pathogens with high sensitivity (1.31 fg/mL) and specificity. Besides, the microfluidic channel offers a promising solution for point-of-care detection. © 2023 SPIE.

A Point-of-care Biosensor with Subwavelength Grating Waveguide-based Micro-ring Resonator for Detection of COVID-19

We present an on-chip optical biosensor for the detection of COVID-19. The subwavelength grating waveguide-based micro-ring resonator with high sensitivity and low limit of detection integrates with microfludic channel, which promises clinical utility in point-of-care diagnostic. © Optica Publishing Group 2022, © 2022 The Author(s)